Targeted Feature Detection for Data-Dependent Shotgun Proteomics
نویسندگان
چکیده
منابع مشابه
Targeted Feature Detection for Data-Dependent Shotgun Proteomics
Label-free quantification of shotgun LC-MS/MS data is the prevailing approach in quantitative proteomics but remains computationally nontrivial. The central data analysis step is the detection of peptide-specific signal patterns, called features. Peptide quantification is facilitated by associating signal intensities in features with peptide sequences derived from MS2 spectra; however, missing ...
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ژورنال
عنوان ژورنال: Journal of Proteome Research
سال: 2017
ISSN: 1535-3893,1535-3907
DOI: 10.1021/acs.jproteome.7b00248